Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
nreBHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)    
Predicted Functional Partners:
uhpA_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
uhpA
Response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.853
narL
Two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.817
rcsB
Transcriptional regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
 
 
 0.816
sirA
Response regulator; In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.782
AKL37889.1
Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.730
AKL34195.1
Aerobic respiration control sensor protein ArcB; Sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.712
hoxN
Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NiCoT transporter (TC 2.A.52) family.
      
 0.710
AKL37888.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.706
AKL33941.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.684
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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