STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crlHypothetical protein; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (132 aa)    
Predicted Functional Partners:
frsA
Fermentation/respiration switch protein; Forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0255 family.
 
     0.835
ytfK
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.767
yieM
Hypothetical protein; Contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.757
cybC
Cytochrome b562; Electron transport protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.744
AKL36734.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
zapC
Cell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
  
     0.725
zapB
Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.703
lpp
Major outer membrane lipoprotein; interacts with peptidoglycan to maintain the integrity of the cell envelope; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.683
AKL36920.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0227 family.
  
     0.675
yijD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.641
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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