STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDF80320.1methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (162 aa)    
Predicted Functional Partners:
SDF86334.1
DNA-3-methyladenine glycosylase II.
 
 
 0.961
SDF80285.1
MFS transporter, FSR family, fosmidomycin resistance protein.
       0.784
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
   0.623
SDF66449.1
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   0.623
SDF07225.1
Nucleotide-binding universal stress protein, UspA family.
  
    0.621
SDF48015.1
DNA polymerase I.
   
 
 0.609
SDF73509.1
Nucleotide-binding universal stress protein, UspA family.
  
    0.569
SDF90852.1
DNA polymerase-4; Belongs to the DNA polymerase type-Y family.
 
   
 0.482
SDF80353.1
Zn-dependent protease (includes SpoIVFB).
       0.479
SDF80387.1
tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.472
Your Current Organism:
Desulfovibrio legallii
NCBI taxonomy Id: 571438
Other names: CCUG 54389, D. legallii, DSM 19129, Desulfovibrio legallii corrig. Thabet et al. 2013, Desulfovibrio legallis, Desulfovibrio sp. H1, strain H1
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