node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEA06886.1 | SEA52415.1 | SAMN05421743_102364 | SAMN05421743_105174 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.446 |
SEA06886.1 | SEA72379.1 | SAMN05421743_102364 | SAMN05421743_107141 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.458 |
SEA06886.1 | SEB03349.1 | SAMN05421743_102364 | SAMN05421743_11389 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Flagellar motor switch protein FliG. | 0.866 |
SEA06886.1 | guaB | SAMN05421743_102364 | SAMN05421743_10264 | DNA-binding transcriptional regulator, XRE-family HTH domain. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.690 |
SEA06886.1 | ndk | SAMN05421743_102364 | SAMN05421743_106113 | DNA-binding transcriptional regulator, XRE-family HTH domain. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.749 |
SEA06886.1 | ribBA | SAMN05421743_102364 | SAMN05421743_107139 | DNA-binding transcriptional regulator, XRE-family HTH domain. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.899 |
SEA34133.1 | SEA72353.1 | SAMN05421743_10465 | SAMN05421743_107140 | Riboflavin kinase / FMN adenylyltransferase. | Riboflavin synthase. | 0.696 |
SEA34133.1 | SEA72379.1 | SAMN05421743_10465 | SAMN05421743_107141 | Riboflavin kinase / FMN adenylyltransferase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.908 |
SEA34133.1 | guaB | SAMN05421743_10465 | SAMN05421743_10264 | Riboflavin kinase / FMN adenylyltransferase. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.411 |
SEA34133.1 | ribBA | SAMN05421743_10465 | SAMN05421743_107139 | Riboflavin kinase / FMN adenylyltransferase. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.905 |
SEA34133.1 | ribH | SAMN05421743_10465 | SAMN05421743_107138 | Riboflavin kinase / FMN adenylyltransferase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.915 |
SEA52415.1 | SEA06886.1 | SAMN05421743_105174 | SAMN05421743_102364 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | DNA-binding transcriptional regulator, XRE-family HTH domain. | 0.446 |
SEA52415.1 | SEA72379.1 | SAMN05421743_105174 | SAMN05421743_107141 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.886 |
SEA52415.1 | ribBA | SAMN05421743_105174 | SAMN05421743_107139 | Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.860 |
SEA72353.1 | SEA34133.1 | SAMN05421743_107140 | SAMN05421743_10465 | Riboflavin synthase. | Riboflavin kinase / FMN adenylyltransferase. | 0.696 |
SEA72353.1 | SEA72379.1 | SAMN05421743_107140 | SAMN05421743_107141 | Riboflavin synthase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
SEA72353.1 | SEB02560.1 | SAMN05421743_107140 | SAMN05421743_11340 | Riboflavin synthase. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.696 |
SEA72353.1 | ndk | SAMN05421743_107140 | SAMN05421743_106113 | Riboflavin synthase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.422 |
SEA72353.1 | ribBA | SAMN05421743_107140 | SAMN05421743_107139 | Riboflavin synthase. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
SEA72353.1 | ribH | SAMN05421743_107140 | SAMN05421743_107138 | Riboflavin synthase. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.999 |