STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEQ41779.1Phenylalanine 4-hydroxylase. (582 aa)    
Predicted Functional Partners:
SEQ42190.1
Pterin-4-alpha-carbinolamine dehydratase.
 
 0.975
SEQ37624.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase /chorismate mutase.
     
 0.731
SEQ72362.1
Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase.
     
 0.693
hutH
Histidine ammonia-lyase.
   
 
 0.678
hisC
Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.658
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
   
 
 0.658
SEQ51965.1
2-iminobutanoate/2-iminopropanoate deaminase.
   
 
  0.623
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
    
  0.621
SEQ41740.1
Polyketide cyclase / dehydrase and lipid transport.
       0.578
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
     
 0.554
Your Current Organism:
Piscibacillus halophilus
NCBI taxonomy Id: 571933
Other names: CCM 7596, DSM 21633, JCM 15721, LMG 24786, LMG:24786, P. halophilus, Piscibacillus halophilus Amoozegar et al. 2009, Piscibacillus sp. HS224, strain HS224
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