node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SKB34442.1 | SKB34618.1 | SAMN05661099_0728 | SAMN05661099_0750 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.800 |
SKB34442.1 | SKB65928.1 | SAMN05661099_0728 | SAMN05661099_2134 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | D-3-phosphoglycerate dehydrogenase. | 0.886 |
SKB34442.1 | SKB91823.1 | SAMN05661099_0728 | SAMN05661099_3460 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Cystathionine beta-synthase. | 0.890 |
SKB34442.1 | eno | SAMN05661099_0728 | SAMN05661099_1718 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.822 |
SKB34442.1 | glyA | SAMN05661099_0728 | SAMN05661099_2753 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.873 |
SKB34442.1 | gpmI | SAMN05661099_0728 | SAMN05661099_0226 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.820 |
SKB34442.1 | mqnA | SAMN05661099_0728 | SAMN05661099_0727 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Chorismate dehydratase; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.843 |
SKB34442.1 | mqnE | SAMN05661099_0728 | SAMN05661099_0729 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Aminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.843 |
SKB34442.1 | pgk | SAMN05661099_0728 | SAMN05661099_3360 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.822 |
SKB34442.1 | serC | SAMN05661099_0728 | SAMN05661099_0751 | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.891 |
SKB34618.1 | SKB34442.1 | SAMN05661099_0750 | SAMN05661099_0728 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | 0.800 |
SKB34618.1 | SKB65928.1 | SAMN05661099_0750 | SAMN05661099_2134 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | D-3-phosphoglycerate dehydrogenase. | 0.989 |
SKB34618.1 | SKB91823.1 | SAMN05661099_0750 | SAMN05661099_3460 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Cystathionine beta-synthase. | 0.569 |
SKB34618.1 | gpmI | SAMN05661099_0750 | SAMN05661099_0226 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.886 |
SKB34618.1 | serC | SAMN05661099_0750 | SAMN05661099_0751 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.998 |
SKB65928.1 | SKB34442.1 | SAMN05661099_2134 | SAMN05661099_0728 | D-3-phosphoglycerate dehydrogenase. | Probable phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. | 0.886 |
SKB65928.1 | SKB34618.1 | SAMN05661099_2134 | SAMN05661099_0750 | D-3-phosphoglycerate dehydrogenase. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.989 |
SKB65928.1 | SKB91823.1 | SAMN05661099_2134 | SAMN05661099_3460 | D-3-phosphoglycerate dehydrogenase. | Cystathionine beta-synthase. | 0.898 |
SKB65928.1 | glyA | SAMN05661099_2134 | SAMN05661099_2753 | D-3-phosphoglycerate dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.872 |
SKB65928.1 | gpmI | SAMN05661099_2134 | SAMN05661099_0226 | D-3-phosphoglycerate dehydrogenase. | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.925 |