STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB63674.1HSP20 family protein; Belongs to the small heat shock protein (HSP20) family. (145 aa)    
Predicted Functional Partners:
clpB
ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.752
SKB94366.1
ATP-dependent Clp protease ATP-binding subunit ClpC; Belongs to the ClpA/ClpB family.
  
 
 0.752
SKB63688.1
Hypothetical protein.
       0.645
SKB75127.1
Hypothetical protein.
   
 
 0.615
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
  
  
 0.511
SKB30257.1
Regulatory protein, luxR family; Manually curated.
    
   0.495
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.492
SKB89048.1
Molecular chaperone HscA; Belongs to the heat shock protein 70 family.
  
 
 0.492
SKB36221.1
Molecular chaperone HtpG.
   
 
 0.450
SKB40557.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.450
Your Current Organism:
Pedobacter luteus
NCBI taxonomy Id: 572036
Other names: DSM 22385, KCTC 22699, P. luteus, Pedobacter luteus Oh et al. 2013, Pedobacter sp. B4a-b5, Pedobacter sp. N7d-4, strain N7d-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.