STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKB72518.15-formyltetrahydrofolate cyclo-ligase; Manually curated; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (192 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.955
purN
Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.916
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
 
  
 0.573
efp
Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
       0.564
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
   
 
 0.543
SKB31614.1
Molybdenum cofactor biosynthesis protein MoaC.
  
  
 0.532
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
    
  0.444
SKB63196.1
Rhomboid-like protein.
  
    0.431
SKB63234.1
Membrane associated serine protease, rhomboid family.
  
    0.431
SKB74150.1
Membrane associated serine protease, rhomboid family.
  
    0.431
Your Current Organism:
Pedobacter luteus
NCBI taxonomy Id: 572036
Other names: DSM 22385, KCTC 22699, P. luteus, Pedobacter luteus Oh et al. 2013, Pedobacter sp. B4a-b5, Pedobacter sp. N7d-4, strain N7d-4
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