STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVAG_185390Histone H3, embryonic, putative. (134 aa)    
Predicted Functional Partners:
TVAG_100580
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.993
TVAG_014920
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.993
TVAG_026390
Histone H2B; Belongs to the histone H2B family.
   
 0.959
TVAG_321390
Histone H2B, testis, putative; Belongs to the histone H2B family.
   
 0.959
TVAG_021440
Histone H2A; Belongs to the histone H2A family.
   
 0.945
TVAG_447860
Histone H2A; Belongs to the histone H2A family.
   
 0.945
TVAG_495500
Actin family protein; Belongs to the actin family.
   
 0.945
TVAG_105970
Histone H2A; Belongs to the histone H2A family.
   
 0.945
TVAG_328410
RNA polymerase Rpb3/Rpb11 dimerisation domain containing protein.
   
 0.939
TVAG_379530
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.933
Your Current Organism:
Trichomonas vaginalis
NCBI taxonomy Id: 5722
Other names: T. vaginalis, Tritrichomonas vaginalis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.