STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVAG_185870Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (435 aa)    
Predicted Functional Partners:
TVAG_058790
WD_REPEATS_REGION domain-containing protein.
   
 0.920
TVAG_385620
WD_REPEATS_REGION domain-containing protein.
   
 0.920
TVAG_252660
HDAC_interact domain-containing protein.
   
 0.912
TVAG_439490
HDAC_interact domain-containing protein.
   
 0.912
TVAG_188020
Chromo domain-containing protein.
   
 0.884
TVAG_219240
Uncharacterized protein.
   
 0.884
TVAG_021600
PHD-finger family protein.
   
 0.873
TVAG_385560
PHD-finger family protein.
   
 0.873
TVAG_299140
2-hydroxyacid dehydrogenase HI1556, putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.871
TVAG_100580
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.869
Your Current Organism:
Trichomonas vaginalis
NCBI taxonomy Id: 5722
Other names: T. vaginalis, Tritrichomonas vaginalis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.