STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TVAG_201990HECT domain-containing protein. (1093 aa)    
Predicted Functional Partners:
TVAG_379650
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.987
TVAG_202470
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.987
TVAG_126330
U-box domain containing protein.
   
 0.972
TVAG_221650
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.971
TVAG_062270
Ubiquitin carrier protein, putative; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.967
TVAG_036330
HECT domain-containing protein.
   
 
0.916
TVAG_198290
Ubiquitin conjugating enzyme, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.901
TVAG_452760
Bendless protein, putative; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.901
TVAG_191220
Ubiquitin-conjugating enzyme family protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.901
TVAG_312130
Ubiquitin-conjugating enzyme family protein.
   
 0.901
Your Current Organism:
Trichomonas vaginalis
NCBI taxonomy Id: 5722
Other names: T. vaginalis, Tritrichomonas vaginalis
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.