Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
znuCHigh-affinity Zn transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (248 aa)    
Predicted Functional Partners:
znuB
High-affinity Zn transport protein (ABC superfamily, membrane); COG1108.
 
 0.999
znuA
High-affinity Zn transport protein (ABC superfamily, peri_bind); COG4531; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.999
yfeD
Chelated iron ABC transporter, permease protein; COG1108.
 
 
 0.886
yfeC
Chelated iron transport system membrane protein; COG1108.
  
 
 0.871
yfeA
Chelated iron ABC transporter, periplasmic iron binding protein; COG0803; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.808
ubiB
2-octaprenylphenol hydroxylase of ubiquinone biosynthetic pathway; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
      0.700
HDEF_0652
Putative M23 peptidase family protein; COG0739.
  
    0.527
lpxM
Myristoyl-acyl carrier protein (ACP)-dependent acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
 
     0.461
fur
Transcriptional repressor of iron transport (Fur family); COG0735; Belongs to the Fur family.
  
  
 0.409
lolB
Outer membrane component involved in lipoprotein localization; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
     0.405
Your Current Organism:
Hamiltonella defensa
NCBI taxonomy Id: 572265
Other names: C. Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa str. 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa strain 5AT (Acyrthosiphon pisum)
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