close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P1APSE-2 prophage; cI. (260 aa)    
Predicted Functional Partners:
P3
APSE-2 prophage; predicted P-loop ATPase.
 
     0.762
P2
APSE-2 prophage: cro.
       0.570
HDEF_1456
Conserved hypothetical phage protein, KilA domain protein.
  
    0.534
HDEF_0408
Conserved hypothetical phage protein.
 
     0.520
P42
APSE-2 prophage; DNA binding protein Roi.
 
     0.503
P43
APSE-2 prophage; conserved hypothetical / Antirepressor.
  
    0.496
HDEF_0293
Hypothetical protein.
  
     0.451
amiD_1
Putative amidase and lipoprotein; COG3023.
  
    0.422
amiD_2
Putative amidase and lipoprotein; COG3023.
  
    0.422
tolC
Outer membrane channel; Tolerance to colicin E1, segregation of daughter chromosomes, role in organic solvent tolerance; COG1538.
  
     0.415
Your Current Organism:
Hamiltonella defensa
NCBI taxonomy Id: 572265
Other names: C. Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa str. 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa strain 5AT (Acyrthosiphon pisum)
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.