rnpA protein (Hamiltonella defensa) - STRING interaction network

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rnpA

RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (115 aa)

Predicted Functional Partners:

rpmH

0.994

HDEF_2010

0.980

yidC

0.977

rpsT

0.849

rpmB

0.832

rpsJ

0.820

rplC

0.817

rplD

0.795

rpsL

0.793

rpsP

0.793

Your Current Organism:

Hamiltonella defensa

NCBI taxonomy Id: 572265
Other names: C. Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa str. 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa strain 5AT (Acyrthosiphon pisum)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HDEF_2010	rnpA	HDEF_2010	HDEF_2011	Conserved hypothetical phage protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.980
HDEF_2010	rplD	HDEF_2010	HDEF_1865	Conserved hypothetical phage protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.	50S ribosomal subunit protein L4, regulates expression of S10 operon; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.	0.515
HDEF_2010	rpmH	HDEF_2010	HDEF_2012	Conserved hypothetical phage protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.	50S ribosomal subunit protein L34; COG0230; Belongs to the bacterial ribosomal protein bL34 family.	0.852
HDEF_2010	yidC	HDEF_2010	HDEF_2009	Conserved hypothetical phage protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.	Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.966
rnpA	HDEF_2010	HDEF_2011	HDEF_2010	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	Conserved hypothetical phage protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.	0.980
rnpA	rplC	HDEF_2011	HDEF_1866	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.817
rnpA	rplD	HDEF_2011	HDEF_1865	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	50S ribosomal subunit protein L4, regulates expression of S10 operon; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.	0.795
rnpA	rpmB	HDEF_2011	HDEF_1914	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	50S ribosomal subunit protein L28; COG0227; Belongs to the bacterial ribosomal protein bL28 family.	0.832
rnpA	rpmH	HDEF_2011	HDEF_2012	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	50S ribosomal subunit protein L34; COG0230; Belongs to the bacterial ribosomal protein bL34 family.	0.994
rnpA	rpsJ	HDEF_2011	HDEF_1867	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.820
rnpA	rpsL	HDEF_2011	HDEF_0721	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.793
rnpA	rpsP	HDEF_2011	HDEF_2326	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	30S ribosomal subunit protein S16; COG0228; Belongs to the bacterial ribosomal protein bS16 family.	0.793
rnpA	rpsT	HDEF_2011	HDEF_0369	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA.	0.849
rnpA	yidC	HDEF_2011	HDEF_2009	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.977
rplC	rnpA	HDEF_1866	HDEF_2011	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	RNase P, protein C5 component, processes tRNA, 4.5S RNA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.	0.817
rplC	rplD	HDEF_1866	HDEF_1865	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	50S ribosomal subunit protein L4, regulates expression of S10 operon; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.	0.999
rplC	rpmB	HDEF_1866	HDEF_1914	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	50S ribosomal subunit protein L28; COG0227; Belongs to the bacterial ribosomal protein bL28 family.	0.995
rplC	rpmH	HDEF_1866	HDEF_2012	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	50S ribosomal subunit protein L34; COG0230; Belongs to the bacterial ribosomal protein bL34 family.	0.961
rplC	rpsJ	HDEF_1866	HDEF_1867	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.999
rplC	rpsL	HDEF_1866	HDEF_0721	50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.997

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