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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmuVHemin ABC transporter, ATP-binding; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (276 aa)    
Predicted Functional Partners:
hmuT
Hemin ABC transporter, periplasmic hemin-binding; COG4558.
 
 
 0.994
hmuS
Hemin transport; COG3720.
  
 0.989
hmuU
Hemin ABC transporter, permease; COG0609; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.989
fecD
Citrate-dependent iron (III) transport protein (ABC superfamily, membrane); COG0609; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.951
hmuR
TonB-dependent hemin receptor; COG1629.
 
   
 0.834
mrcB
Bifunctional penicillin-binding protein 1b: glycosyl transferase (N-terminal); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
      0.638
Your Current Organism:
Hamiltonella defensa
NCBI taxonomy Id: 572265
Other names: C. Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa str. 5AT (Acyrthosiphon pisum), Candidatus Hamiltonella defensa strain 5AT (Acyrthosiphon pisum)
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