STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_0317Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131:IPR001714:IPR000587; KEGG: cma:Cmaq_1605 peptidase M24; PFAM: peptidase M24; creatinase; SPTR: A8M9V7 Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. (364 aa)    
Predicted Functional Partners:
Vdis_0318
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR001345:IPR013078; KEGG: cma:Cmaq_0729 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: A8MCQ9 Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family.
     
 0.683
Vdis_0319
KEGG: cma:Cmaq_1037 hypothetical protein; SPTR: A8MDL0 Putative uncharacterized protein.
       0.631
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.516
Vdis_2469
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: pai:PAE3023 carbon nitrogen hydrolase, conjectural; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Q8ZTZ2 Carbon nitrogen hydrolase, conjectural; PFAM: Carbon-nitrogen hydrolase.
 
 
 0.477
Vdis_0316
KEGG: cma:Cmaq_0754 hypothetical protein; SPTR: A8MCT4 Putative uncharacterized protein.
       0.473
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
  
 0.470
Vdis_2026
COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: cma:Cmaq_0501 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: A8MC40 Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase.
 
 
 0.441
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.437
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.437
Vdis_1286
COGs: COG0060 Isoleucyl-tRNA synthetase; InterProIPR001412:IPR002300:IPR013155:IPR009008:IPR 009080:IPR014729:IPR015905:IPR002301; KEGG: cma:Cmaq_1197 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: A8ME18 Isoleucyl-tRNA synthetase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.432
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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