STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Vdis_0629Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: kcr:Kcr_1035 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: B1L5Q2 Threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme. (380 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.977
Vdis_0971
COGs: COG1171 Threonine dehydratase; InterPro IPR005789:IPR001926:IPR002912; KEGG: cma:Cmaq_0945 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: A8MDC1 Threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine synthase; threonine dehydratase, medium form.
  
 
 0.959
Vdis_1871
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR001926; KEGG: tro:trd_0006 threonine ammonia-lyase, biosynthetic; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: B9L1A5 Threonine ammonia-lyase, biosynthetic; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
  
 
 0.959
Vdis_2491
Pyridoxal-5'-phosphate-dependent protein beta subunit; COGs: COG1171 Threonine dehydratase; InterPro IPR001926; KEGG: cma:Cmaq_0128 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: A8MA47 Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme.
  
 
 0.959
Vdis_0606
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
  
 
0.926
Vdis_2493
COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: cma:Cmaq_1074 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: A8MDP7 Pyridoxal-5'-phosphate-dependent protein beta subunit; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
 
  
 
0.919
Vdis_0607
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR016040:IPR019811:IPR005106:IPR001342; KEGG: sto:ST1519 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: C1TQI7 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
 
 
 0.855
Vdis_0631
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: cma:Cmaq_1080 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: A8MDQ3 Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
 
  
 0.808
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
  
 0.756
Vdis_0609
COGs: COG0527 Aspartokinase; InterPro IPR001048; KEGG: cma:Cmaq_0009 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Aspartate kinase; SPTR: A8M9I2 Aspartate kinase; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase.
  
 
 0.755
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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