STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_0647KEGG: pis:Pisl_0583 hypothetical protein; SPTR: A1RS29 Putative uncharacterized protein. (192 aa)    
Predicted Functional Partners:
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.792
Vdis_0646
COGs: COG0023 Translation initiation factor 1 (eIF-1/SUI1) and related protein; InterPro IPR001950:IPR017228; KEGG: cma:Cmaq_0760 translation initiation factor SUI1; PFAM: translation initiation factor SUI1; SPTR: A8MCU0 Translation initiation factor SUI1; PFAM: Translation initiation factor SUI1; TIGRFAM: translation initation factor SUI1, putative, prokaryotic; Belongs to the SUI1 family.
       0.615
Vdis_0645
KEGG: cma:Cmaq_0761 hypothetical protein; SPTR: A8MCU1 Putative uncharacterized protein.
       0.613
Vdis_0644
COGs: COG1095 DNA-directed RNA polymerase subunit E'; InterProIPR003029:IPR005576:IPR016027:IPR012340:IPR 004519; KEGG: cma:Cmaq_1136 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein; PRIAM: DNA-directed RNA polymerase; SPTR: A8MDV7 DNA-directed RNA polymerase; TIGRFAM: DNA-directed RNA polymerase; PFAM: S1 RNA binding domain; RNA polymerase Rpb7-like, N-terminal domain; TIGRFAM: DNA-directed RNA polymerase (rpoE), archaeal and eukaryotic form.
       0.501
Vdis_0649
KEGG: sbn:Sbal195_2788 hypothetical protein; SPTR: A9KTQ0 Putative uncharacterized protein.
       0.411
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.