STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_0720Protein synthesis factor GTP-binding protein; COGs: COG5257 Translation initiation factor 2 gamma subunit (eIF-2gamma; GTPase); InterProIPR000795:IPR004161:IPR015256:IPR009000:IPR 009001; KEGG: cma:Cmaq_1531 translation initiation factor IF-2 subunit gamma; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Initiation factor eIF2 gamma domain protein; SPTR: A8M9D5 Protein synthesis factor GTP-binding; PFAM: Elongation factor Tu domain 2; Elongation factor Tu GTP binding domain; Initiation factor eIF2 gamma, C terminal. (414 aa)    
Predicted Functional Partners:
Vdis_2147
COGs: COG1601 Translation initiation factor 2 beta subunit (eIF-2beta)/eIF-5 N-terminal domain; InterPro IPR002735:IPR016189:IPR016190; KEGG: cma:Cmaq_0582 translation initiation factor IF-2 subunit beta; PFAM: Translation initiation factor IF2/IF5; SMART: Translation initiation factor IF2/IF5; SPTR: A8MCB7 Translation initiation factor IF2/IF5; PFAM: Domain found in IF2B/IF5; TIGRFAM: translation initiation factor aIF-2, beta subunit, putative.
  
 0.992
Vdis_2062
COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR012340:IPR003029:IPR011488:IPR016027; KEGG: cma:Cmaq_1359 translation initiation factor 2, alpha subunit; PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SPTR: A8M8W6 Translation initiation factor 2, alpha subunit; PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain.
  
 0.990
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 0.974
rps6e
COGs: COG2125 Ribosomal protein S6E (S10); InterPro IPR001377:IPR018282; KEGG: pcl:Pcal_0821 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; SPTR: A3MUD0 30S ribosomal protein S6e; PFAM: Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
 0.974
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 0.972
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
 0.966
infB
Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
 
 0.966
rps4e
COGs: COG1471 Ribosomal protein S4E; InterPro IPR002942:IPR013843:IPR013845:IPR000876; KEGG: cma:Cmaq_1832 30S ribosomal protein S4e; PFAM: Ribosomal protein S4E, central domain protein; RNA-binding S4 domain protein; Ribosomal protein S4E domain protein; SMART: RNA-binding S4 domain protein; SPTR: A8MB20 30S ribosomal protein S4e; PFAM: S4 domain; Ribosomal family S4e; RS4NT (NUC023) domain; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 0.965
rps15
COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR012606:IPR000589:IPR009068; KEGG: pcl:Pcal_1173 30S ribosomal protein S15P; PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; SPTR: A3MVD1 30S ribosomal protein S15P/S13e; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15.
 
 0.965
rps3ae
COGs: COG1890 Ribosomal protein S3AE; InterPro IPR001593:IPR018281; KEGG: cma:Cmaq_1755 30S ribosomal protein S3Ae; PFAM: ribosomal protein S3Ae; SPTR: A8MAK1 Ribosomal protein S3Ae; PFAM: Ribosomal S3Ae family; Belongs to the eukaryotic ribosomal protein eS1 family.
 
 0.965
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.