STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_1183Protein of unknown function DUF99; COGs: COG1628 conserved hypothetical protein; InterPro IPR002802; KEGG: cma:Cmaq_1894 hypothetical protein; PFAM: protein of unknown function DUF99; SPTR: A8MBH8 Putative uncharacterized protein; PFAM: Protein of unknown function DUF99; Belongs to the UPF0215 family. (195 aa)    
Predicted Functional Partners:
ribK
CTP-dependent riboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.
  
     0.616
Vdis_0819
COGs: COG0704 Phosphate uptake regulator; InterPro IPR007159:IPR008170; KEGG: cma:Cmaq_0447 phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SpoVT/AbrB domain protein; SPTR: A8MBU9 Phosphate uptake regulator, PhoU; PFAM: PhoU domain; SpoVT / AbrB like domain.
 
     0.538
Vdis_1185
KEGG: cma:Cmaq_0117 hypothetical protein; SPTR: A8MA38 Putative uncharacterized protein.
       0.503
tiaS
Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
     0.500
Vdis_1844
COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004821:IPR006418:IPR014729:IPR004820; KEGG: cma:Cmaq_1647 nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinamide-nucleotide adenylyltransferase; SPTR: A8M9Z9 Nicotinamide-nucleotide adenylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
     0.481
Vdis_1854
Transcription factor CBF/NF-Y/histone domain protein; COGs: COG2036 Histones H3 and H4; InterPro IPR009072:IPR003958; KEGG: cma:Cmaq_1704 transcription factor CBF/NF-Y histone; PFAM: Transcription factor CBF/NF-Y/histone domain protein; SPTR: A8MAF0 Transcription factor CBF/NF-Y histone; PFAM: Histone-like transcription factor (CBF/NF-Y) and archaeal histone.
 
     0.473
Vdis_2289
Protein of unknown function ATP binding protein; COGs: COG1855 ATPase (PilT family); InterPro IPR004088:IPR006596:IPR003593:IPR004130; KEGG: cma:Cmaq_0298 ATPase; PFAM: protein of unknown function ATP binding; SMART: AAA ATPase; Nucleotide binding protein PINc; SPTR: A8MB56 Type II secretion system protein E; PFAM: Type II/IV secretion system protein.
  
   
 0.463
Vdis_0844
Cytidyltransferase-related domain protein; COGs: COG1056 Nicotinamide mononucleotide adenylyltransferase; InterPro IPR004820:IPR014729:IPR004821; KEGG: cma:Cmaq_0276 cytidyltransferase-like protein; PFAM: cytidylyltransferase; PRIAM: Nicotinamide-nucleotide adenylyltransferase; SPTR: A8MAT8 Cytidyltransferase-related domain; TIGRFAM: cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinamide-nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
     0.459
Vdis_0595
COGs: COG1829 kinase (sugar kinase superfamily); InterPro IPR020568:IPR017441:IPR006204:IPR012043; KEGG: cma:Cmaq_1785 GHMP kinase; PFAM: GHMP kinase; SPTR: A8MAX9 GHMP kinase.
  
     0.456
Vdis_1251
Metallophosphoesterase; COGs: COG1407 ICC-like phosphoesterase; InterPro IPR004843; KEGG: cma:Cmaq_1551 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: A8M9F5 Metallophosphoesterase; TIGRFAM: putative phosphoesterase, SbcD/Mre11-related.
  
     0.443
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.