STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vdis_1616Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR001176:IPR004839:IPR004838:IPR015421:IPR 015424; KEGG: cma:Cmaq_0323 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8MB81 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. (405 aa)    
Predicted Functional Partners:
Vdis_0680
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: cma:Cmaq_1344 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Chorismate mutase; SPTR: A8M8V1 Prephenate dehydratase; PFAM: Prephenate dehydratase; ACT domain.
 
 
 0.976
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: cma:Cmaq_0765 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: A8MCU4 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; manually curated; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.935
Vdis_1757
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557:IPR001236:IPR016040:IPR015955; KEGG: cma:Cmaq_1675 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase; SPTR: A8MAC1 Malate dehydrogenase; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent; Belongs to the LDH/MDH superfamily.
  
 0.932
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.927
Vdis_1840
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterProIPR006095:IPR006097:IPR006096:IPR014362:IPR 016040; KEGG: pis:Pisl_1816 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; SPTR: A1RVI3 Glu/Leu/Phe/Val dehydrogenase, C terminal; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.926
Vdis_1723
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759:IPR013027; KEGG: cma:Cmaq_0612 putative glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A8MCE7 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.924
Vdis_2492
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR015421:IPR015424; KEGG: cma:Cmaq_0127 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: A8MA46 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
  
  
 
0.914
Vdis_0203
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR015424:IPR015421:IPR004839; KEGG: cma:Cmaq_0643 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: A8MCH7 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
  
  
 
0.912
Vdis_1361
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: cma:Cmaq_0591 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: A8MCC6 Rhodanese domain protein; PFAM: Rhodanese-like domain.
    
 0.911
Vdis_1372
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001307:IPR001763; KEGG: cma:Cmaq_0591 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: A8MCC6 Rhodanese domain protein; PFAM: Rhodanese-like domain.
    
 0.911
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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