STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (243 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.924
Vdis_1517
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611:IPR002139; KEGG: pis:Pisl_1117 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: A1RTK6 PfkB domain protein; PFAM: pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.922
Vdis_0220
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterProIPR009014:IPR015941:IPR005474:IPR005475:IPR 005476; KEGG: cma:Cmaq_0809 transketolase central region; PFAM: Transketolase central region; Transketolase domain protein; SPTR: A8MCY8 Transketolase central region; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase.
  
 
 0.921
Vdis_0369
COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915:IPR013785; KEGG: cma:Cmaq_1259 fructose-bisphosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Fructose-bisphosphate aldolase; SPTR: P58315 Fructose-bisphosphate aldolase class 1; PFAM: DeoC/LacD family aldolase.
    
 0.921
Vdis_2334
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR016162:IPR016161:IPR015590; KEGG: smr:Smar_0084 nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: A3DKN7 Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
  
 0.917
fbp
Fructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
    
 0.911
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.884
Vdis_2389
Transcriptional regulator, RpiR family; InterPro IPR001347:IPR019490; KEGG: cma:Cmaq_1967 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: A8MBZ9 Bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase.
  
 
 0.867
gap
Glyceraldehyde-3-phosphate dehydrogenase, type II; COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR006436:IPR020831:IPR016040:IPR020828:IPR 020829:IPR020830; KEGG: pcl:Pcal_0632 glyceraldehyde-3-phosphate dehydrogenase; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating); SPTR: A3MTU1 Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, t [...]
    
 0.866
Vdis_0717
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015794:IPR015813:IPR015795:IPR 011037:IPR001697; KEGG: cma:Cmaq_0580 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: A8MCB5 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
  
 0.855
Your Current Organism:
Vulcanisaeta distributa
NCBI taxonomy Id: 572478
Other names: V. distributa DSM 14429, Vulcanisaeta distributa DSM 14429, Vulcanisaeta distributa str. DSM 14429, Vulcanisaeta distributa strain DSM 14429
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