STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (498 aa)    
Predicted Functional Partners:
ADO77323.1
Alpha/beta hydrolase fold protein; COGs: COG2267 Lysophospholipase; InterPro IPR000073; KEGG: dat:HRM2_06410 PldB; PFAM: alpha/beta hydrolase fold; SPTR: PldB; PFAM: Putative lysophospholipase.
 
  
 0.937
plsY
Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.916
ADO77601.1
HtrA2 peptidase; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001254:IPR001478:IPR001940; KEGG: hor:Hore_00650 2-alkenal reductase; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: 2-alkenal reductase; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF).
   
 0.825
ADO76510.1
Hypothetical protein; InterPro IPR002110:IPR020683:IPR018114; KEGG: sbl:Sbal_0761 ankyrin domain-containing protein; SPTR: Ankyrin domain protein; PFAM: Ankyrin repeat.
   
 0.804
ADO76193.1
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129:IPR000909; KEGG: cac:CAC0430 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphodiester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
 
  
 0.691
ADO76560.1
COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR000909:IPR004129; KEGG: psp:PSPPH_3162 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase family.
 
  
 0.678
ADO76170.1
KEGG: lwe:lwe0305 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.627
ADO76172.1
FAD dependent oxidoreductase; COGs: COG0579 dehydrogenase; InterPro IPR006076:IPR007419; KEGG: hut:Huta_0683 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase.
  
  
 0.623
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.621
ADO77702.1
COGs: COG0469 Pyruvate kinase; InterProIPR018209:IPR015793:IPR015794:IPR008279:IPR 001697; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.621
Your Current Organism:
Halanaerobium praevalens
NCBI taxonomy Id: 572479
Other names: H. praevalens DSM 2228, Halanaerobium praevalens ATCC 33744, Halanaerobium praevalens DSM 2228, Halanaerobium praevalens GSL, Halanaerobium praevalens str. DSM 2228, Halanaerobium praevalens strain DSM 2228
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