STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO77698.1PHP domain protein; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR003141; KEGG: hor:Hore_19230 biotin (acetyl-CoA carboxylase) synthetase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Biotin (Acetyl-CoA carboxylase) synthetase; PFAM: PHP domain. (249 aa)    
Predicted Functional Partners:
ADO77697.1
Conserved hypothetical protein; COGs: COG1242 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR005911; KEGG: hor:Hore_11990 radical SAM protein, TIGR01212 family; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM protein, TIGR01212 family; TIGRFAM: conserved hypothetical protein; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family.
       0.770
ADO77706.1
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004365:IPR003141:IPR 004805; KEGG: hor:Hore_03140 DNA polymerase III catalytic subunit, DnaE type; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III catalytic subunit, DnaE type; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: DNA-directed DNA polymerase III (polc).
 
   
 0.557
ADO77699.1
Amino acid ABC transporter ATP-binding protein, PAAT family; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: cno:NT01CX_0136 ABC-type polar amino acid transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type polar amino acid transport system, ATPase component; PFAM: ABC transporter.
       0.510
ADO77700.1
Amino acid ABC transporter membrane protein, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: ckr:CKR_0629 hypothetical protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Putative uncharacterized protein; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family.
       0.500
ADO77696.1
Metallophosphoesterase; InterPro IPR004843; KEGG: drm:Dred_1478 hypothetical protein; PFAM: metallophosphoesterase; SPTR: Putative uncharacterized protein; PFAM: Calcineurin-like phosphoesterase.
  
    0.498
ADO77701.1
Amino acid ABC transporter substrate-binding protein, PAAT family; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR018313:IPR001638:IPR001320; KEGG: cbi:CLJ_B0518 polar amino acid uptake ABC transporter, PAAT family, amino acid-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: Polar amino acid uptake ABC transporter, PAAT family, amino acid-binding protein; PFAM: Bacterial extracellular solute-binding proteins, [...]
       0.485
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.432
ADO77702.1
COGs: COG0469 Pyruvate kinase; InterProIPR018209:IPR015793:IPR015794:IPR008279:IPR 001697; KEGG: hor:Hore_03220 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
    0.418
Your Current Organism:
Halanaerobium praevalens
NCBI taxonomy Id: 572479
Other names: H. praevalens DSM 2228, Halanaerobium praevalens ATCC 33744, Halanaerobium praevalens DSM 2228, Halanaerobium praevalens GSL, Halanaerobium praevalens str. DSM 2228, Halanaerobium praevalens strain DSM 2228
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