| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADG91800.1 | ADG92149.1 | Arnit_0133 | Arnit_0484 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 0.837 |
| ADG92144.1 | ADG92149.1 | Arnit_0479 | Arnit_0484 | Protein of unknown function DUF448; InterPro IPR007393; KEGG: abu:Abu_2042 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: A8EWD6 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF448). | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 0.825 |
| ADG92149.1 | ADG91800.1 | Arnit_0484 | Arnit_0133 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.837 |
| ADG92149.1 | ADG92144.1 | Arnit_0484 | Arnit_0479 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | Protein of unknown function DUF448; InterPro IPR007393; KEGG: abu:Abu_2042 hypothetical protein; PFAM: protein of unknown function DUF448; SPTR: A8EWD6 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF448). | 0.825 |
| ADG92149.1 | ADG93328.1 | Arnit_0484 | Arnit_1674 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 0.997 |
| ADG92149.1 | ADG94594.1 | Arnit_0484 | Arnit_2946 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; COGs: COG0439 Biotin carboxylase; InterProIPR013817:IPR013815:IPR016185:IPR011761:IPR 003135; KEGG: abu:Abu_2250 ATP-grasp domain-containing protein; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: A8EWZ0 ATP-grasp (A) domain protein; PFAM: ATP-grasp domain. | 0.837 |
| ADG92149.1 | ADG94660.1 | Arnit_0484 | Arnit_3012 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783:IPR017938; KEGG: abu:Abu_2211 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: A8EWV1 Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.999 |
| ADG92149.1 | eno | Arnit_0484 | Arnit_2956 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.958 |
| ADG92149.1 | ribA | Arnit_0484 | Arnit_1041 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.997 |
| ADG92149.1 | ribB | Arnit_0484 | Arnit_1709 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| ADG92149.1 | ribB-2 | Arnit_0484 | Arnit_2720 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.982 |
| ADG92149.1 | ribH | Arnit_0484 | Arnit_2288 | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.990 |
| ADG93328.1 | ADG92149.1 | Arnit_1674 | Arnit_0484 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 0.997 |
| ADG93328.1 | ADG94660.1 | Arnit_1674 | Arnit_3012 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783:IPR017938; KEGG: abu:Abu_2211 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: A8EWV1 Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | 0.993 |
| ADG93328.1 | ribA | Arnit_1674 | Arnit_1041 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.903 |
| ADG93328.1 | ribB | Arnit_1674 | Arnit_1709 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.998 |
| ADG93328.1 | ribB-2 | Arnit_1674 | Arnit_2720 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. | 0.982 |
| ADG93328.1 | ribH | Arnit_1674 | Arnit_2288 | COGs: COG0807 GTP cyclohydrolase II; InterPro IPR000926; KEGG: cco:CCC13826_0883 GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; PRIAM: GTP cyclohydrolase II; SPTR: A7ZCL6 GTP cyclohydrolase-2; TIGRFAM: GTP cyclohydrolase II; PFAM: GTP cyclohydrolase II; TIGRFAM: GTP cyclohydrolase II. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.968 |
| ADG94594.1 | ADG92149.1 | Arnit_2946 | Arnit_0484 | ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; COGs: COG0439 Biotin carboxylase; InterProIPR013817:IPR013815:IPR016185:IPR011761:IPR 003135; KEGG: abu:Abu_2250 ATP-grasp domain-containing protein; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: A8EWZ0 ATP-grasp (A) domain protein; PFAM: ATP-grasp domain. | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 0.837 |
| ADG94660.1 | ADG92149.1 | Arnit_3012 | Arnit_0484 | COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783:IPR017938; KEGG: abu:Abu_2211 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: A8EWV1 Riboflavin synthase, alpha subunit; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit. | Riboflavin biosynthesis protein RibD; COGs: COG0117 Pyrimidine deaminase; InterPro IPR004794:IPR016193:IPR002125:IPR002734; KEGG: abu:Abu_2046 bifunctional riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; SPTR: A8EWE0 Bifunctional riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin biosynthesis protein RibD. | 0.999 |