| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADG92414.1 | ADG92415.1 | Arnit_0749 | Arnit_0750 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 0.674 |
| ADG92414.1 | ADG92418.1 | Arnit_0749 | Arnit_0753 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | 0.543 |
| ADG92414.1 | mnmA | Arnit_0749 | Arnit_0747 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.716 |
| ADG92414.1 | mnmA-2 | Arnit_0749 | Arnit_0748 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.699 |
| ADG92414.1 | prs | Arnit_0749 | Arnit_0746 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.553 |
| ADG92415.1 | ADG92414.1 | Arnit_0750 | Arnit_0749 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | 0.674 |
| ADG92415.1 | ADG92418.1 | Arnit_0750 | Arnit_0753 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | 0.673 |
| ADG92415.1 | metG | Arnit_0750 | Arnit_1718 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.447 |
| ADG92415.1 | mnmA | Arnit_0750 | Arnit_0747 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.636 |
| ADG92415.1 | mnmA-2 | Arnit_0750 | Arnit_0748 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.618 |
| ADG92415.1 | prs | Arnit_0750 | Arnit_0746 | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.550 |
| ADG92418.1 | ADG92414.1 | Arnit_0753 | Arnit_0749 | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR002052; KEGG: abu:Abu_0486 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: A8ES37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydrop [...] | 0.543 |
| ADG92418.1 | ADG92415.1 | Arnit_0753 | Arnit_0750 | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000994:IPR001131; KEGG: abu:Abu_0487 prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: peptidase M24; SPTR: A8ES38 Prolidase (Xaa-Pro dipeptidase) (PepQ); PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; Belongs to the peptidase M24B family. | 0.673 |
| ADG92418.1 | mnmA | Arnit_0753 | Arnit_0747 | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.557 |
| ADG92418.1 | mnmA-2 | Arnit_0753 | Arnit_0748 | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.530 |
| ADG92418.1 | prs | Arnit_0753 | Arnit_0746 | Signal peptide peptidase SppA, 36K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004635:IPR002142; KEGG: abu:Abu_0490 protease IV (PspA); PFAM: peptidase S49; SPTR: A8ES41 Protease IV (PspA); TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.438 |
| lepA | metG | Arnit_0744 | Arnit_1718 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.581 |
| lepA | mnmA | Arnit_0744 | Arnit_0747 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.558 |
| lepA | mnmA-2 | Arnit_0744 | Arnit_0748 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.580 |
| lepA | mnmE | Arnit_0744 | Arnit_2368 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.410 |