STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG93039.1Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: tdn:Suden_1428 hydrogenase formation HypD protein; PFAM: hydrogenase formation HypD protein; SPTR: Q30QM6 Hydrogenase formation HypD protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family. (374 aa)    
Predicted Functional Partners:
ADG93038.1
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR000276:IPR001109; KEGG: abu:Abu_1407 hydrogenase expression/formation protein HypC; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: A8EUN8 Hydrogenase expression/formation protein HypC; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
 
 0.998
ADG93041.1
Hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854:IPR016188; KEGG: abu:Abu_1401 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; SPTR: B6BMU9 Hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE.
 
 
 0.998
ADG93037.1
Hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR003495:IPR012202:IPR004392; KEGG: abu:Abu_1408 hydrogenase expression/formation protein HypB; PFAM: cobalamin synthesis protein P47K; SPTR: A8EUN9 Hydrogenase expression/formation protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB.
 
  
 0.979
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.925
ADG93028.1
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
  
 0.885
ADG93017.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR018194:IPR001501; KEGG: abu:Abu_1436 Ni/Fe-dependent hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: A8EUR7 Ni/Fe-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase.
 
 
 0.827
ADG93040.1
COGs: COG0518 GMP synthase - Glutamine amidotransferase domain; InterPro IPR000991:IPR017926; KEGG: cph:Cpha266_0839 glutamine amidotransferase; PFAM: glutamine amidotransferase class-I; SPTR: A1BER3 Glutamine amidotransferase class-I; PFAM: Glutamine amidotransferase class-I.
       0.773
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
  
 0.758
ADG91706.1
COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR018194:IPR001501; KEGG: sun:SUN_1653 Ni-Fe hydrogenase, large subunit; PFAM: nickel-dependent hydrogenase large subunit; SPTR: B6BMJ3 Quinone-reactive Ni/Fe-hydrogenase large chain; PFAM: Nickel-dependent hydrogenase.
 
 
 0.716
ADG93016.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137; KEGG: abu:Abu_1437 Ni/Fe-dependent hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: A8EUR8 Ni/Fe-dependent hydrogenase, small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA).
 
  
 0.696
Your Current Organism:
Arcobacter nitrofigilis
NCBI taxonomy Id: 572480
Other names: A. nitrofigilis DSM 7299, Arcobacter nitrofigilis DSM 7299, Arcobacter nitrofigilis str. DSM 7299, Arcobacter nitrofigilis strain DSM 7299
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