STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Coexpression
Experiments
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[Homology]
Score
ADG93665.1Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR016040:IPR002198; KEGG: Pc21g08110; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: B6HLK5 Pc21g08110 protein; PFAM: short chain dehydrogenase. (231 aa)    
Predicted Functional Partners:
nuoC
NADH-ubiquinone oxidoreductase chain 49kDa; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.797
ADG93005.1
Enoyl-CoA hydratase/isomerase; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR006180:IPR001753:IPR006176:IPR006108:IPR 016040:IPR013328:IPR008927; KEGG: pin:Ping_2604 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; SPTR: B6BLQ4 Fatty acid oxidation complex alpha subunit; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
  
 0.733
ADG93865.1
Amino acid adenylation domain protein; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR010071:IPR016039:IPR016035:IPR016040:IPR 009081:IPR016036:IPR014030:IPR014031:IPR014043:IPR013217:I PR013968:IPR006163:IPR001242:IPR013624:IPR000873:IPR001031 :IPR016038:IPR001227:IPR006162:IPR020845:IPR018201; KEGG: pmr:PMI2600 non-ribosomal peptide synthase (siderophore synthase); PFAM: AMP-dependent synthetase and ligase; Beta-ketoacyl synthase; Acyl transferase; Methyltransferase type 12; KR domain protein; phosphopantetheine-binding; condensation domain protein; Non-rib [...]
 
 
 0.695
ADG93864.1
Amino acid adenylation domain protein; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR009081:IPR020459:IPR001242:IPR 013624:IPR000873:IPR006163:IPR020845; KEGG: npu:Npun_CR074 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Non-ribosomal peptide synthetase; phosphopantetheine-binding; SPTR: Q8GAQ3 BarG; TIGRFAM: amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; Nonribosomal peptide synthase; T [...]
 
 
 0.635
ADG92835.1
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073:IPR000639; KEGG: abu:Abu_1144 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: A8ETY0 Alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold.
 
 0.540
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.529
ADG92910.1
Ankyrin; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110:IPR020683; KEGG: abu:Abu_1550 ankyrin repeat-containing protein; PFAM: Ankyrin; SMART: Ankyrin; SPTR: A8EV26 Ankyrin repeat protein; PFAM: Ankyrin repeat.
  
 0.517
ADG93666.1
KEGG: dps:DP0703 hypothetical protein; SPTR: Q6AQE1 Putative uncharacterized protein.
       0.516
ADG93006.1
COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155:IPR016038:IPR016039; KEGG: pin:Ping_2605 acetyl-CoA acetyltransferases; PRIAM: Acetyl-CoA C-acyltransferase; SPTR: B6BLQ5 3-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.506
ADG91735.1
Ankyrin; InterPro IPR020683:IPR002110; KEGG: ava:Ava_3944 ankyrin; PFAM: Ankyrin; SMART: Ankyrin; SPTR: A0YVD4 Putative uncharacterized protein; PFAM: Ankyrin repeat.
  
 0.485
Your Current Organism:
Arcobacter nitrofigilis
NCBI taxonomy Id: 572480
Other names: A. nitrofigilis DSM 7299, Arcobacter nitrofigilis DSM 7299, Arcobacter nitrofigilis str. DSM 7299, Arcobacter nitrofigilis strain DSM 7299
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