STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADG93793.14Fe-4S ferredoxin iron-sulfur binding domain protein; InterPro IPR001450:IPR017896:IPR017900; KEGG: abu:Abu_0854 2-oxoglutarate-acceptor oxidoreductase subunit OorD; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A8ET40 OorD subunit of 2-oxoglutarate:acceptor oxidoreductase. (104 aa)    
Predicted Functional Partners:
ADG93796.1
COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR002869:IPR019752; KEGG: abu:Abu_0857 2-oxoglutarate-acceptor oxidoreductase subunit OorC; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: A8ET43 OorC subunit of 2-oxoglutarate:acceptor oxidoreductase; PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase.
 
 
 0.994
nuoC
NADH-ubiquinone oxidoreductase chain 49kDa; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 0.993
ADG93794.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR009014:IPR002880:IPR015941; KEGG: abu:Abu_0855 2-oxoglutarate-acceptor oxidoreductase subunit OorA; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A8ET41 OorA subunit of 2-oxoglutarate:acceptor oxidoreductase; PFAM: domain; Transketolase, C-terminal domain.
 
 0.992
ADG93795.1
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: cco:CCC13826_1293 2-oxoglutarate-acceptor oxidoreductase subunit OorB; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: C2A2C6 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
 
 0.990
ADG94254.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR000089:IPR004099:IPR016156:IPR011053:IPR 012999:IPR003016:IPR006258:IPR013027:IPR000815; KEGG: abu:Abu_1474 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; biotin/lipoyl attachment domain-containing protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A8EUV5 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-di [...]
   
 0.946
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.923
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.918
ADG92400.1
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268:IPR001501:IPR001135; KEGG: cco:CCC13826_0711 DNA-3-methyladenine glycosylase I; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; nickel-dependent hydrogenase large subunit; NADH-ubiquinone oxidoreductase chain 49kDa; SPTR: A7ZBL3 Hydrogenase-4 component G; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
  
 
 0.912
ADG93575.1
Isocitrate dehydrogenase, NADP-dependent; COGs: COG2838 Monomeric isocitrate dehydrogenase; InterPro IPR004436; KEGG: abu:Abu_1314 isocitrate dehydrogenase; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; PRIAM: Isocitrate dehydrogenase (NADP(+)); SPTR: A8EUE7 Isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Monomeric isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family.
     
  0.900
ADG94303.1
COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023:IPR012336; KEGG: abu:Abu_0312 NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: A8ERL3 NADH-quinone oxidoreductase, E subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit.
  
 0.849
Your Current Organism:
Arcobacter nitrofigilis
NCBI taxonomy Id: 572480
Other names: A. nitrofigilis DSM 7299, Arcobacter nitrofigilis DSM 7299, Arcobacter nitrofigilis str. DSM 7299, Arcobacter nitrofigilis strain DSM 7299
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