STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADG94347.1Lysine exporter protein (LYSE/YGGA); COGs: COG1279 Lysine efflux permease; InterPro IPR001123; KEGG: asu:Asuc_0217 lysine exporter protein LysE/YggA; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: C9PP62 LysE family transporter; PFAM: LysE type translocator. (205 aa)    
Predicted Functional Partners:
ADG94348.1
Multiple antibiotic resistance (MarC)-related protein; COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: nam:NAMH_0417 hypothetical protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: C1ZYU9 Putative uncharacterized protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427.
       0.773
ADG94349.1
Polar amino acid ABC transporter, inner membrane subunit; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR000515:IPR010065; KEGG: wsu:WS0280 ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: C1ZYL8 Amino acid ABC transporter membrane protein, PAAT family; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family.
       0.773
ADG94350.1
Extracellular solute-binding protein family 3; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR018313:IPR001638:IPR001320; KEGG: nam:NAMH_0584 binding component of abc transporter; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: C1ZYL7 Amino acid ABC transporter substrate-binding protein, PAAT family; PFAM: Bacterial extracellular solute-binding proteins, family 3.
       0.773
ADG94351.1
ABC transporter related protein; COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: nam:NAMH_0585 amino acid permease ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: B9L8P3 Amino acid permease ATP-binding protein; PFAM: ABC transporter.
       0.752
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.548
ADG94352.1
InterPro IPR000620; KEGG: wsu:WS0276 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Q7MSN2 Putative uncharacterized protein; PFAM: EamA-like transporter family.
       0.513
ADG93643.1
InterPro IPR000620; KEGG: lpf:lpl2401 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: C9PGX7 Permease; PFAM: EamA-like transporter family.
  
     0.424
ADG94345.1
Dihydrofolate reductase region; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.423
ADG91765.1
InterPro IPR000620; KEGG: yen:YE3697 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: B9C9T6 Probable amino-acid metabolite efflux pump; PFAM: EamA-like transporter family.
  
     0.408
Your Current Organism:
Arcobacter nitrofigilis
NCBI taxonomy Id: 572480
Other names: A. nitrofigilis DSM 7299, Arcobacter nitrofigilis DSM 7299, Arcobacter nitrofigilis str. DSM 7299, Arcobacter nitrofigilis strain DSM 7299
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