STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO81804.1Serine dehydratase alpha chain; COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: dde:Dde_3034 L-serine ammonia-lyase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; SPTR: C6JLF6 L-serine ammonia-lyase; PFAM: Serine dehydratase alpha chain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form. (402 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.964
ADO83012.1
L-threonine ammonia-lyase; COGs: COG1171 Threonine dehydratase; InterPro IPR000634:IPR005789:IPR001926:IPR002912; KEGG: trq:TRQ2_0579 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: C3WB15 Threonine dehydratase catabolic; TIGRFAM: threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form.
  
 
 0.924
ADO82181.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451:IPR018357; KEGG: vcj:VCD_003411 serine acetyltransferase; SPTR: B6VZQ5 Putative uncharacterized protein; PFAM: Bacterial transferase hexapeptide (three repeats).
     
 0.909
ADO82386.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451:IPR018357:IPR005881; KEGG: cno:NT01CX_1391 serine acetyltransferase; PRIAM: Serine O-acetyltransferase; SPTR: B1B7H4 Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
     
 0.909
ADO82902.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462:IPR004533; KEGG: fnu:FN0991 CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: C3WCT4 CDP-diacylglycerol-serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
  0.900
ADO82453.1
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR019811:IPR016040; KEGG: lba:Lebu_0845 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; PRIAM: Homoserine dehydrogenase; SPTR: C7N9C2 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
   
 
 0.829
ADO82785.1
COGs: COG0460 Homoserine dehydrogenase; InterPro IPR016040:IPR005106; KEGG: cbl:CLK_1105 homoserine dehydrogenase; PFAM: homoserine dehydrogenase NAD-binding; SPTR: B1KS27 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase.
   
 
 0.829
metAA1
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
     
 0.819
ADO82455.1
COGs: COG2334 Putative homoserine kinase type II (protein kinase fold); InterPro IPR002575:IPR011009; KEGG: fnu:FN0922 homoserine kinase; PFAM: aminoglycoside phosphotransferase; PRIAM: Homoserine kinase; SPTR: C6JLU8 Homoserine kinase; PFAM: Phosphotransferase enzyme family; TIGRFAM: homoserine kinase, Neisseria type.
     
  0.800
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
       0.503
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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