STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO81956.1RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: lba:Lebu_0387 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: C3WFR8 23S rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferas [...] (236 aa)    
Predicted Functional Partners:
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
   0.746
ADO81822.1
Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR020103:IPR006145; KEGG: fnu:FN0651 ribosomal large subunit pseudouridine synthase D; PFAM: pseudouridine synthase; SPTR: C6JLM4 Pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family.
 
 
 0.720
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR002302:IPR014729:IPR009008:IPR009080:IPR 001412:IPR015413:IPR013155; KEGG: fnu:FN1517 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); SPTR: C6JLT2 Leucine-tRNA ligase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
   0.720
ADO82161.1
COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942:IPR020103:IPR006145:IPR006224; KEGG: fnu:FN1026 tRNA pseudouridine synthase A; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: C6JNL9 Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family; Belongs to the pseudouridine synthase RluA family.
 
 
 0.691
ADO83482.1
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
 
 0.679
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR002308:IPR009080:IPR015803:IPR015273:IPR 014729; KEGG: fnu:FN1579 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: C6JHY4 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.679
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 
 0.667
ADO81957.1
RNA polymerase, sigma-24 subunit, ECF subfamily; COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterProIPR014284:IPR016371:IPR013325:IPR016032:IPR 000943:IPR007627:IPR013249; KEGG: pjd:Pjdr2_5700 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: C6JLT1 RNA polymerase sigma-H factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-H factor.
  
    0.653
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.637
ADO82317.1
Ribosome biogenesis GTPase YqeH; COGs: COG1161 GTPase; InterPro IPR006073:IPR002917:IPR019988; KEGG: fnu:FN1072 GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: C3WDB2 GTP-binding protein; TIGRFAM: ribosome biogenesis GTPase YqeH; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTPase YqeH; small GTP-binding protein domain.
  
 
 0.636
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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