STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO82039.1COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR013785:IPR007197:IPR006638; KEGG: fnu:FN1612 coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: C6JJF3 Iron-sulfur dehydrogenase; PFAM: Radical SAM superfamily. (464 aa)    
Predicted Functional Partners:
ADO82048.1
Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 
0.928
ADO82040.1
KEGG: fnu:FN1611 competence protein; SPTR: C6JJF4 Competence protein ComEA; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region.
 
     0.755
ADO82038.1
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR001992:IPR018076:IPR003004; KEGG: hor:Hore_05990 Tfp pilus biogenesis protein PilC; PFAM: Type II secretion system F domain; SPTR: B8D2C9 Tfp pilus biogenesis protein PilC; PFAM: Bacterial type II secretion system protein F domain.
       0.723
ADO82037.1
Pilus retraction ATPase PilT; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR006321:IPR001482:IPR003593; KEGG: ate:Athe_1883 twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: B9MKW3 Twitching motility protein; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
       0.718
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
    0.682
hldD
ADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
  
    0.563
ADO82034.1
Nucleoside 2-deoxyribosyltransferase; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base; Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
 
     0.551
ADO82331.1
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002869:IPR009014:IPR002880:IPR019752:IPR 019456:IPR001450:IPR017896:IPR017900:IPR015941:IPR011895; KEGG: fnu:FN1170 pyruvate-flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C6JQE8 Pyruvate-flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; P [...]
  
  
 0.529
ADO83116.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: aoe:Clos_1831 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: C3WCD5 Radical SAM domain-containing protein; PFAM: Radical SAM superfamily; B12 binding domain.
 
  
 0.500
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.473
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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