STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO82315.1Integrase family protein; COGs: COG4974 Site-specific recombinase XerD; InterProIPR011010:IPR010998:IPR004107:IPR002104:IPR 013762; KEGG: lba:Lebu_1112 integrase family protein; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: C6JQF7 Integrase/recombinase; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; Belongs to the 'phage' integrase family. (297 aa)    
Predicted Functional Partners:
hslV
ATP dependent peptidase CodWX, CodW component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.798
trmFO
Gid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
  
    0.743
ADO82317.1
Ribosome biogenesis GTPase YqeH; COGs: COG1161 GTPase; InterPro IPR006073:IPR002917:IPR019988; KEGG: fnu:FN1072 GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: C3WDB2 GTP-binding protein; TIGRFAM: ribosome biogenesis GTPase YqeH; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTPase YqeH; small GTP-binding protein domain.
     
 0.713
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.654
ADO82312.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: lba:Lebu_1110 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: C6JQG0 Smf protein; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
   
 0.585
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.548
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
 
   
 0.479
ADO83299.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: fnu:FN1368 ComF operon protein 3; PFAM: phosphoribosyltransferase; SPTR: C6JJ96 COMF operon protein 3; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
  
    0.466
ADO82829.1
DNA methylase N-4/N-6 domain protein; COGs: COG0863 DNA modification methylase; InterProIPR001091:IPR002052:IPR015840:IPR003115:IPR 002941; KEGG: seu:SEQ_0163 phage DNA methylase; PFAM: DNA methylase N-4/N-6 domain protein; ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: C0MBJ3 Phage DNA methylase; PFAM: ParB-like nuclease domain; DNA methylase; Belongs to the N(4)/N(6)-methyltransferase family.
  
  
 0.457
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
    0.453
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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