STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO82447.1COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003594:IPR005467:IPR004358; KEGG: fnu:FN0066 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: C6JJX8 Sensor histidine kinase (Fragment); PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (803 aa)    
Predicted Functional Partners:
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
       0.800
ADO82446.1
Tex-like protein; COGs: COG2183 Transcriptional accessory protein; InterProIPR018974:IPR003029:IPR006641:IPR016027:IPR 012340; KEGG: fnu:FN0065 transcription accessory protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: C6JJX7 Transcriptional accessory protein; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region.
       0.780
ADO83052.1
TPR repeat-containing protein; InterPro IPR011990:IPR001440:IPR019734:IPR013026; KEGG: fnu:FN1836 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SPTR: C3WC18 Tetratricopeptide repeat family protein.
 
     0.751
ADO83165.1
Putative anti-sigma regulatory factor, serine/threonine protein kinase; InterPro IPR003594; KEGG: fnu:FN1915 anti-sigma B factor; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: C6JJP7 Anti-sigma B factor; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
   
 0.735
ADO82271.1
COGs: COG2067 Long-chain fatty acid transport protein; InterPro IPR005017; KEGG: lba:Lebu_1782 membrane protein involved in aromatic hydrocarbon degradation; PFAM: membrane protein involved in aromatic hydrocarbon degradation; SPTR: C6JK47 Outer membrane protein P1; PFAM: Outer membrane protein transport protein (OMPP1/FadL/TodX).
 
    0.733
ADO83105.1
COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR009019; KEGG: fnu:FN0285 RNA binding protein; SPTR: C3WDQ6 RNA binding protein; Belongs to the UPF0109 family.
 
     0.733
ADO83362.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR003661:IPR003594:IPR001789:IPR004010:IPR 011006:IPR009082:IPR004358:IPR005467; KEGG: aoe:Clos_0389 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Cache domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: C6Q0M6 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyr [...]
 
 
 0.695
ADO81791.1
KEGG: fnu:FN0001 chromosomal replication initiator protein DnaA; SPTR: C6JLE5 Chromosomal replication initiator protein dnaA.
  
     0.671
ADO82416.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR011006; KEGG: dsy:DSY4121 hypothetical protein; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: C6JN38 DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 
 0.642
ADO82070.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR003594:IPR011006:IPR 009082:IPR003661:IPR004358; KEGG: aoe:Clos_0389 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: C6Q0M6 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPa [...]
 
 
 
0.634
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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