STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adeCOGs: COG1001 Adenine deaminase; InterPro IPR006680:IPR011059; KEGG: cpe:CPE1268 adenine deaminase; PFAM: amidohydrolase; PRIAM: Adenine deaminase; SPTR: Q8XKX4 Adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (573 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.972
ADO81920.1
Molybdopterin dehydrogenase FAD-binding protein; COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR016166:IPR016169:IPR005107:IPR002346; KEGG: swo:Swol_1137 dehydrogenase; PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: C6DXN3 Molybdopterin dehydrogenase, FAD-binding; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain.
 
  
  0.923
ADO83100.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: lba:Lebu_1306 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: C4BWF2 Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.911
ADO83101.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: spe:Spro_3998 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: A8GJ03 Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.911
ADO83240.1
COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR018016:IPR004402:IPR000845; KEGG: cpr:CPR_1391 purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; SPTR: A8UMT3 Purine nucleoside phosphorylase; TIGRFAM: purine nucleoside phosphorylase; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD).
   
 
 0.909
ADO82218.1
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.907
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
ADO82511.1
Extracellular solute-binding protein family 1; COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR006059:IPR001188; KEGG: cpf:CPF_1477 ABC transporter, substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Q0TR20 ABC transporter, substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein.
 
  
 0.884
ADO82513.1
Binding-protein-dependent transport systems inner membrane component; COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: cpf:CPF_1479 ABC transporter, permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Q0TR18 ABC transporter, permease protein; PFAM: Binding-protein-dependent transport system inner membrane component.
 
   
 0.801
ADO82509.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR011059; KEGG: cpe:CPE1267 hypothetical protein; PFAM: amidohydrolase; SPTR: Q8XKX5 Putative uncharacterized protein CPE1267; PFAM: Amidohydrolase family.
 
   
 0.786
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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