STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: lba:Lebu_2138 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: C4C7M4 Glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
  
 0.978
ADO82408.1
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289:IPR013785; KEGG: lba:Lebu_2198 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: C6JKV0 Fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist.
  
 
 0.954
ADO83141.1
Fructose-1,6-bisphosphatase, class II; COGs: COG1494 Fructose-1 6-bisphosphatase/sedoheptulose 1 7-bisphosphatase and related protein; InterPro IPR004464; KEGG: fnu:FN1159 fructose 1,6-bisphosphatase II; PFAM: GlpX family protein; PRIAM: Fructose-bisphosphatase; SPTR: C3WCB5 Fructose-1,6-bisphosphatase; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: Bacterial fructose-1,6-bisphosphatase, glpX-encoded; TIGRFAM: fructose-1,6-bisphosphatase, class II.
   
 
 0.938
ADO82526.1
COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR002173:IPR017583; KEGG: cpr:CPR_0551 1-phosphofructokinase; PFAM: PfkB domain protein; SPTR: Q0SVH1 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
     
 0.935
fbp
Fructose-16-bisphosphatase; COGs: COG3855 conserved hypothetical protein; InterPro IPR009164:IPR013838; KEGG: cbf:CLI_0596 fructose-1,6-bisphosphatase; PFAM: fructose-16-bisphosphatase; SPTR: A7GAS1 Fructose-1,6-bisphosphatase class 3; PFAM: Firmicute fructose-1,6-bisphosphatase.
  
  
 0.931
ADO82200.1
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterProIPR011051:IPR005835:IPR001538:IPR014710:IPR 006375; KEGG: mvu:Metvu_0406 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: C9RFB4 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltran [...]
    
 0.923
mtlD
D-mannitol 1-phosphate 5-dehydrogenase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterProIPR000669:IPR008927:IPR016040:IPR013328:IPR 013131:IPR013118; KEGG: aat:D11S_1815 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: C9R5U0 Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain.
    
 0.916
ADO82535.1
Mannose-6-phosphate isomerase, type 1; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250:IPR014628:IPR011051:IPR014710; KEGG: lba:Lebu_2134 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; SPTR: C6JP17 Mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
    
 0.914
ADO82906.1
COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: tpd:Teth39_0491 transketolase domain-containing protein; PFAM: Transketolase domain protein; SPTR: C6PK27 Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain.
    
 0.906
ADO83264.1
COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: fnu:FN0294 transketolase subunit A; PFAM: Transketolase domain protein; SPTR: C6JIV3 Transketolase; PFAM: Transketolase, thiamine diphosphate binding domain.
    
 0.906
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.