STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO83130.1Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterProIPR001405:IPR014013:IPR001650:IPR006554:IPR 014001:IPR006555; KEGG: lba:Lebu_1866 helicase C2; SMART: helicase c2; DEAD-like helicase; Helicase-like, DEXD box c2 type; SPTR: C6JKU1 ATP-dependent helicase; PFAM: DEAD_2; DEAD/DEAH box helicase; TIGRFAM: DnaQ family exonuclease/DinG family helicase, putative. (815 aa)    
Predicted Functional Partners:
ADO82790.1
Type III restriction protein res subunit; COGs: COG1061 DNA or RNA helicase of superfamily II; InterPro IPR014021:IPR001650:IPR014001:IPR006935; KEGG: ctc:CTC00657 DNA/RNA helicase; PFAM: type III restriction protein res subunit; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Q897S2 DNA/RNA helicase; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit.
   
 0.987
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.960
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.957
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.943
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.873
ADO83254.1
SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330:IPR001650:IPR014021:IPR014001; KEGG: fnu:FN1386 SWF/SNF family helicase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: C6JJJ0 SWF/SNF family helicase; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
 
 
 0.826
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.801
ADO83129.1
Metal dependent phosphohydrolase; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterProIPR006675:IPR011624:IPR011621:IPR006674:IPR 003607; KEGG: fnu:FN0745 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase 7TM intracellular region; metal-dependent phosphohydrolase 7TM extracellular region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: C6JKU0 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD h [...]
 
     0.704
ADO83346.1
ATP-dependent DNA helicase, RecQ-like protein; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR002121:IPR011545:IPR 018982:IPR006293:IPR018329:IPR010997:IPR014021; KEGG: cbi:CLJ_B1040 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: helicase domain protein; DEAD-like helicase; HRDC domain protein; SPTR: B1QK91 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; [...]
 
 0.656
ADO83054.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.626
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.