STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADO83405.1Ham1 family protein; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637; KEGG: sai:Saci_0849 nucleoside-triphosphatase; PFAM: Ham1 family protein; SPTR: Q4JAG3 Nucleoside-triphosphatase; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family. (187 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.926
ADO82309.1
NUDIX hydrolase; InterPro IPR020476:IPR015797:IPR000086:IPR020084; KEGG: lba:Lebu_0666 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: NUDIX hydrolase; SPTR: C7IKH6 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
  
 
 0.911
ADO83100.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: lba:Lebu_1306 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: C4BWF2 Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.908
ADO83101.1
COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: spe:Spro_3998 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: A8GJ03 Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.908
ADO81825.1
5'-Nucleotidase domain protein; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterProIPR008334:IPR004843:IPR018392:IPR002482:IPR 006179; KEGG: cdl:CDR20291_2424 putative membrane-associated 5'-nucleotidase/phosphoesterase; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: C6JPY3 5'-Nucleotidase domain-containing protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; LysM domain; Belongs to the 5'-nucleotidase family.
  
 
  0.904
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.901
ADO82889.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
  0.900
ADO81800.1
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: fnu:FN2124 hypothetical protein; PFAM: metallophosphoesterase; SPTR: C3WMI3 Phosphodiesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
  
  
 0.517
ADO83122.1
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: ctc:CTC01815 phosphodiesterase; PFAM: metallophosphoesterase; SPTR: Q893K3 Putative phosphoesterase; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
  
  
 0.517
ADO82629.1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550:IPR007553; KEGG: bay:RBAM_000900 hypothetical protein; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; protein of unknown function DUF523; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: C4ID47 Bifunctional folate synthesis protein; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: Protein of unknown function (DUF523); 7,8-dihydro-6-hydroxymethylpterin-pyr [...]
  
  
 0.471
Your Current Organism:
Ilyobacter polytropus
NCBI taxonomy Id: 572544
Other names: I. polytropus DSM 2926, Ilyobacter polytropus DSM 2926, Ilyobacter polytropus str. DSM 2926, Ilyobacter polytropus strain DSM 2926
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