STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADB57719.1PFAM: protein of unknown function DUF87; KEGG: rpt:Rpal_3925 protein of unknown function DUF87. (526 aa)    
Predicted Functional Partners:
ADB57720.1
KEGG: dal:Dalk_1252 AAA ATPase; TIGRFAM: peptidase S16, Lon-like protease; PFAM: peptidase S16 lon domain protein; SMART: AAA ATPase; Hedgehog/intein hint domain protein; Belongs to the peptidase S16 family.
 
     0.754
rad50
SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
 
   
 0.703
ADB57137.1
Conserved hypothetical protein.
   
 
 0.685
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
 
   
 0.634
ADB57721.1
PFAM: Radical SAM domain protein; cobalamin B12- binding domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: dal:Dalk_5142 radical SAM domain protein.
       0.501
ADB57722.1
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mxa:MXAN_6449 B12 binding/radical SAM domain- containing protein.
       0.501
ADB57723.1
Hypothetical protein.
       0.489
ADB57708.1
PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; KEGG: nam:NAMH_1087 hemolysin A.
 
     0.458
Your Current Organism:
Archaeoglobus profundus
NCBI taxonomy Id: 572546
Other names: A. profundus DSM 5631, Archaeoglobus profundus DSM 5631, Archaeoglobus profundus str. DSM 5631, Archaeoglobus profundus strain DSM 5631
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.