Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB57867.1PFAM: NUDIX hydrolase; KEGG: gur:Gura_1829 NUDIX hydrolase. (136 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
     
 0.804
ADB57868.1
Transcription termination factor Tfs; KEGG: DNA-directed RNA polymerase III family protein; K03019 DNA-directed RNA polymerase III subunit C11; TIGRFAM: transcription factor S; PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
       0.798
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: hch:HCH_00294 argininosuccinate lyase.
      0.756
rtcB
PFAM: protein of unknown function UPF0027; SMART: Hedgehog/intein hint domain protein; KEGG: sat:SYN_02046 RtcB protein; Belongs to the RtcB family.
       0.690
ADB58592.1
PFAM: prephenate dehydratase; Prephenate dehydrogenase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: mms:mma_2673 bifunctional chorismate mutase / prephenate dehydratase.
     
 0.583
ADB58512.1
KEGG: pca:Pcar_2283 3-phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD- superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein; HAD- superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3.
     
 0.548
pcn
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
     
 0.522
ADB58499.1
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: nis:NIS_1287 family X DNA polymerase IV.
     
 0.521
ADB58893.1
PFAM: protein of unknown function UPF0066; KEGG: avn:Avin_38460 hypothetical protein.
  
    0.508
ADB57864.1
Hypothetical protein; KEGG: similar to cyclic nucleotide gated channel beta 1.
       0.494
Your Current Organism:
Archaeoglobus profundus
NCBI taxonomy Id: 572546
Other names: A. profundus DSM 5631, Archaeoglobus profundus DSM 5631, Archaeoglobus profundus str. DSM 5631, Archaeoglobus profundus strain DSM 5631
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.