Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (282 aa)    
Predicted Functional Partners:
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
  
 
 0.954
ADB57208.1
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.950
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
  
 
 0.939
ADB58069.1
PFAM: phosphoribosyltransferase; KEGG: mca:MCA2827 phosphoribosyl transferase domain- containing protein.
  
  
 0.748
kptA-2
Phosphotransferase KptA/Tpt1; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
       0.651
ADB58071.1
Conserved hypothetical protein.
       0.651
ADB58592.1
PFAM: prephenate dehydratase; Prephenate dehydrogenase; amino acid-binding ACT domain protein; Chorismate mutase; KEGG: mms:mma_2673 bifunctional chorismate mutase / prephenate dehydratase.
  
  
 0.591
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.539
ADB58067.1
KEGG: dat:HRM2_11690 HysB; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit.
       0.499
ADB58065.1
Cytochrome b subunit of formate dehydrogenase-like protein; KEGG: ppd:Ppro_1576 cytochrome b561.
       0.496
Your Current Organism:
Archaeoglobus profundus
NCBI taxonomy Id: 572546
Other names: A. profundus DSM 5631, Archaeoglobus profundus DSM 5631, Archaeoglobus profundus str. DSM 5631, Archaeoglobus profundus strain DSM 5631
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