Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADB58128.1Cobaltochelatase; PFAM: CobN/magnesium chelatase; KEGG: sfu:Sfum_0496 cobaltochelatase. (1250 aa)    
Predicted Functional Partners:
ADB58129.1
PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; von Willebrand factor type A; KEGG: ppd:Ppro_1261 magnesium chelatase.
 
  
 0.995
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 
 0.962
ADB57361.1
PFAM: ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rpt:Rpal_1693 magnesium chelatase ATPase subunit I.
 
  
 0.887
ADB57333.1
Dehydrogenase (flavoprotein)-like protein; KEGG: nam:NAMH_1575 geranylgeranyl hydrogenase.
 
  
 0.640
ADB57777.1
Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
 
  
 0.626
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.572
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.560
ADB58127.1
PFAM: nucleoside recognition domain protein; KEGG: dal:Dalk_3536 nucleoside recognition domain protein.
 
     0.557
ADB57458.1
Dehydrogenase (flavoprotein)-like protein; KEGG: abu:Abu_0471 hypothetical protein.
  
  
 0.527
ADB57177.1
PFAM: membrane-flanked domain.
  
    0.525
Your Current Organism:
Archaeoglobus profundus
NCBI taxonomy Id: 572546
Other names: A. profundus DSM 5631, Archaeoglobus profundus DSM 5631, Archaeoglobus profundus str. DSM 5631, Archaeoglobus profundus strain DSM 5631
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.