STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (400 aa)    
Predicted Functional Partners:
ADE56311.1
KEGG: dol:Dole_0755 NifU domain-containing protein; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein.
 
 0.999
ADE56312.1
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: gur:Gura_1193 UBA/ThiF-type NAD/FAD binding protein.
   
 0.997
ADE56297.1
PFAM: SirA family protein; KEGG: sfu:Sfum_3169 SirA family protein; Belongs to the sulfur carrier protein TusA family.
   
 0.989
ADE56309.1
KEGG: gur:Gura_3908 BadM/Rrf2 family transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
 
  
 0.963
ADE57180.1
KEGG: sfu:Sfum_3401 selenide, water dikinase; TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.
    
 0.918
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.902
ADE57281.1
KEGG: sfu:Sfum_3402 SirA family protein; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA family protein; Belongs to the sulfur carrier protein TusA family.
   
 
 0.898
ADE58019.1
KEGG: glo:Glov_1241 transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074.
  
  
 0.757
ADE56313.1
TIGRFAM: DNA-3-methyladenine glycosylase I; KEGG: vfi:VF_A0815 3-methyl-adenine DNA glycosylase I, constitutive; PFAM: methyladenine glycosylase.
       0.738
hslU
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
 
  
 0.594
Your Current Organism:
Aminobacterium colombiense
NCBI taxonomy Id: 572547
Other names: A. colombiense DSM 12261, Aminobacterium colombiense DSM 12261, Aminobacterium colombiense str. DSM 12261, Aminobacterium colombiense strain DSM 12261
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