STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (288 aa)    
Predicted Functional Partners:
ADE56652.1
Succinate--CoA ligase (ADP-forming); KEGG: mlo:mlr1324 malate--CoA ligase subunit beta; PFAM: ATP-grasp domain protein; ATP-citrate lyase/succinyl-CoA ligase.
 0.999
ADE56649.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: sfu:Sfum_0017 2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.980
ADE56650.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ppd:Ppro_2324 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.980
ADE57701.1
PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: dat:HRM2_47640 PdhC.
 
 0.967
ADE57201.1
KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain.
  
 0.963
ADE56654.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dal:Dalk_1630 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 0.946
ADE57567.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dps:DP2103 2-oxoacid ferredoxin oxidoreductase, alpha subunit.
  
 
 0.942
ADE56651.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase; KEGG: afw:Anae109_1896 pyruvate ferredoxin/flavodoxin oxidoreductase.
 
 
 0.940
ADE57020.1
TIGRFAM: methylmalonyl-CoA mutase, large subunit; KEGG: gem:GM21_0572 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
    
 0.919
ADE57019.1
PFAM: cobalamin B12-binding domain protein; KEGG: afw:Anae109_1989 cobalamin B12-binding domain- containing protein.
    
 0.918
Your Current Organism:
Aminobacterium colombiense
NCBI taxonomy Id: 572547
Other names: A. colombiense DSM 12261, Aminobacterium colombiense DSM 12261, Aminobacterium colombiense str. DSM 12261, Aminobacterium colombiense strain DSM 12261
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