STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADE56731.1PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: dal:Dalk_5177 single-stranded-DNA-specific exonuclease RecJ. (554 aa)    
Predicted Functional Partners:
ADE56730.1
Hypothetical protein.
       0.818
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.787
ADE57538.1
KEGG: mxa:MXAN_1071 single-strand binding protein; TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n.
 
 
 0.711
ADE56729.1
PFAM: Radical SAM domain protein; KEGG: gsu:GSU0244 radical SAM domain-containing protein.
  
    0.706
ADE56739.1
TIGRFAM: penicillin-binding protein 2; KEGG: gme:Gmet_0928 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
 
    0.670
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
 
     0.655
ADE56735.1
KEGG: afr:AFE_0358 DNA repair protein RadC; TIGRFAM: DNA repair protein RadC; PFAM: DNA repair protein RadC; helix-hairpin-helix motif; Belongs to the UPF0758 family.
 
   
 0.647
ADE56736.1
KEGG: pca:Pcar_1049 rod shape-determining protein MreB; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA.
 
    0.636
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
  
 0.620
ADE56732.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.614
Your Current Organism:
Aminobacterium colombiense
NCBI taxonomy Id: 572547
Other names: A. colombiense DSM 12261, Aminobacterium colombiense DSM 12261, Aminobacterium colombiense str. DSM 12261, Aminobacterium colombiense strain DSM 12261
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