node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE56441.1 | ADE56726.1 | Amico_0296 | Amico_0591 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | 0.939 |
ADE56441.1 | ADE56827.1 | Amico_0296 | Amico_0692 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.509 |
ADE56441.1 | ADE56829.1 | Amico_0296 | Amico_0694 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase, YidC/Oxa1 family; KEGG: sfu:Sfum_2597 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. | 0.990 |
ADE56441.1 | ffh | Amico_0296 | Amico_0551 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.973 |
ADE56441.1 | ftsY | Amico_0296 | Amico_1050 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.974 |
ADE56441.1 | secA | Amico_0296 | Amico_1426 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.993 |
ADE56441.1 | secD | Amico_0296 | Amico_0592 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.921 |
ADE56441.1 | secE | Amico_0296 | Amico_0313 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.998 |
ADE56441.1 | secY | Amico_0296 | Amico_0647 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.993 |
ADE56726.1 | ADE56441.1 | Amico_0591 | Amico_0296 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.939 |
ADE56726.1 | ADE56829.1 | Amico_0591 | Amico_0694 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Membrane protein insertase, YidC/Oxa1 family; KEGG: sfu:Sfum_2597 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. | 0.931 |
ADE56726.1 | ffh | Amico_0591 | Amico_0551 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.930 |
ADE56726.1 | ftsY | Amico_0591 | Amico_1050 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.939 |
ADE56726.1 | secA | Amico_0591 | Amico_1426 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.937 |
ADE56726.1 | secD | Amico_0591 | Amico_0592 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.858 |
ADE56726.1 | secE | Amico_0591 | Amico_0313 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.954 |
ADE56726.1 | secY | Amico_0591 | Amico_0647 | KEGG: bba:Bd2235 preprotein translocase YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.948 |
ADE56827.1 | ADE56441.1 | Amico_0692 | Amico_0296 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.509 |
ADE56827.1 | ADE56828.1 | Amico_0692 | Amico_0693 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.980 |
ADE56827.1 | ADE56829.1 | Amico_0692 | Amico_0694 | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | Membrane protein insertase, YidC/Oxa1 family; KEGG: sfu:Sfum_2597 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein. | 0.972 |