node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADE57003.1 | ADE57645.1 | Amico_0872 | Amico_1528 | TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: afw:Anae109_1161 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein. | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | 0.543 |
ADE57003.1 | ADE57653.1 | Amico_0872 | Amico_1536 | TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: afw:Anae109_1161 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein. | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | 0.539 |
ADE57003.1 | topA | Amico_0872 | Amico_1521 | TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: afw:Anae109_1161 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.536 |
ADE57645.1 | ADE57003.1 | Amico_1528 | Amico_0872 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: afw:Anae109_1161 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein. | 0.543 |
ADE57645.1 | ADE57653.1 | Amico_1528 | Amico_1536 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | 0.903 |
ADE57645.1 | gyrA | Amico_1528 | Amico_0252 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.444 |
ADE57645.1 | lepA | Amico_1528 | Amico_1161 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.655 |
ADE57645.1 | minE | Amico_1528 | Amico_0607 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.472 |
ADE57645.1 | rnc | Amico_1528 | Amico_1060 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.764 |
ADE57645.1 | rnhB | Amico_1528 | Amico_1526 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.885 |
ADE57645.1 | rpmF | Amico_1528 | Amico_1069 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | KEGG: sfu:Sfum_1369 ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; Belongs to the bacterial ribosomal protein bL32 family. | 0.444 |
ADE57645.1 | topA | Amico_1528 | Amico_1521 | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.714 |
ADE57653.1 | ADE57003.1 | Amico_1536 | Amico_0872 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; KEGG: afw:Anae109_1161 putative membrane-associated zinc metalloprotease; SMART: PDZ/DHR/GLGF domain protein. | 0.539 |
ADE57653.1 | ADE57645.1 | Amico_1536 | Amico_1528 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | TIGRFAM: signal peptidase I; KEGG: dvu:DVU0704 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | 0.903 |
ADE57653.1 | fhs | Amico_1536 | Amico_1537 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | KEGG: pmr:PMI0670 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; Belongs to the formate--tetrahydrofolate ligase family. | 0.460 |
ADE57653.1 | gyrA | Amico_1536 | Amico_0252 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.444 |
ADE57653.1 | lepA | Amico_1536 | Amico_1161 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.647 |
ADE57653.1 | minE | Amico_1536 | Amico_0607 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.534 |
ADE57653.1 | rnc | Amico_1536 | Amico_1060 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.677 |
ADE57653.1 | rnhB | Amico_1536 | Amico_1526 | TIGRFAM: signal peptidase I; KEGG: glo:Glov_1621 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.514 |