STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADE57769.1PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: reu:Reut_B5441 uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (331 aa)    
Predicted Functional Partners:
ADE57283.1
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.920
ADE56597.1
KEGG: reu:Reut_B5441 uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
  
 
0.918
ADE57770.1
TIGRFAM: amidohydrolase; KEGG: GSVIVT00034215001; hypothetical protein LOC100251400; PFAM: peptidase M20; peptidase dimerisation domain protein.
       0.603
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.485
ADE57771.1
PFAM: peptidase M24; KEGG: slo:Shew_0955 peptidase M24.
       0.465
ADE57768.1
KEGG: dac:Daci_3752 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
       0.458
nfi
Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
  
    0.445
Your Current Organism:
Aminobacterium colombiense
NCBI taxonomy Id: 572547
Other names: A. colombiense DSM 12261, Aminobacterium colombiense DSM 12261, Aminobacterium colombiense str. DSM 12261, Aminobacterium colombiense strain DSM 12261
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