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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEK30975.1beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (313 aa)    
Predicted Functional Partners:
sucC
Malate thiokinase large subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.977
sucD
Malate thiokinase small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.976
SEL20064.1
L-erythro-3-methylmalyl-CoA dehydratase.
 
 
 0.948
SEK30924.1
Serine-glyoxylate aminotransferase apoenzyme.
 
  
 0.946
SEL20000.1
(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.924
SEK32263.1
Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
 0.914
SEL00819.1
Biotin carboxyl carrier protein /biotin carboxylase.
  
 
  0.911
SEL00998.1
propionyl-CoA carboxylase carboxyltransferase subunit.
    
 0.909
SEK57186.1
beta-methylmalyl-CoA/L-malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.906
SEL10799.1
Hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.903
Your Current Organism:
Roseovarius nanhaiticus
NCBI taxonomy Id: 573024
Other names: CCTCC AB 208317, DSM 29590, LMG 24840, LMG:24840, MCCC 1A03543, R. nanhaiticus, Roseovarius nanhaiticus Wang et al. 2010, Roseovarius sp. NH52J, strain NH52J
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